Posted by: Laurence Harmon on 10/7/2010 | 0 Comments

In biblical times, people were long-lived.  It is said that Adam lived 930 years, and his son, Seth, lived to be 912.  Seth's son, Lamech, lived 777 years, and Noah, Lamech's son, lived to be 950.  Noah's son, Shem, lived to be 600, and his son, Arphaxad, lived 438 years.  Skipping a few generations, Abraham lived to be 175; jumping a few more, Moses lived 120 years. 


Recently, experts have generally agreed that humans have a theoretical maximum lifespan of 125 years--similar to Moses.  Even if that estimate is correct, we know that our health declines many years--even decades--before that. 

Many scientists believe that the 125-year lifespan, as well as the earlier decline in health, is caused by the gradual shortening of our "telomeres," which are the structures at the ends of our chromosomes.  This shortening is believed to be the so-called "clock of aging" in our bodies. 


The good news is that a human cell that does not undergo this shortening will divide indefinitely, which means that it would be literally immortal.  Bottom line:  If we could find a way to stop--or reverse--this shortening, we could live forever!

Enter Sierra Sciences, LLC, a biotechnology company founded in 1999.  The company is dedicated to preventing--or reversing--cellular aging, ultimately curing diseases associated with human aging, including the aging process itself.  Here's how:  Our reproductive cells don't experience shortening of telomeres; they don't age.  They have an enzyme, "telomerase," which re-lengthens the telomeres as they shorten.  Sierra Sciences is searching for pharmaceuticals that will produce telemorase in all our cells. 

If successful, the
Fountain of Youth that Ponce de Leon thought he had found when he landed in St. Augustine, Florida, is actually 2,800 miles northwest, in Reno, Nevada.  That's where you'll find the home of Sierra Sciences.

Posted by: Laurence Harmon on 8/24/2010 | 0 Comments

"New York Times" reports video findings of Columbia U journalism grads who studied the various ways that graying Americans live.  Here's the link:

Dr. Alan J. Hamilton, Director of Boomer-Living, is a graduate of Harvard Medical School and chief of neurosurgery and chairman of the Department of Surgery at the University of Arizona Health Sciences Center.  Here's his advice for fellow aging

We have to take charge of our own health care. Unfortunately, most of our doctors are not health care providers. They were taught to be disease managers. They are interventional practitioners. We see them for an appointment. They recommend tests, or give us medications, or perform procedures but rarely does one single physician develop an integrated picture of who we really are holistically as patients, of where the emotional, physical, and psychological factors meet. They see the flesh of our lives, but not the meat. No one can do that for us. So we need to enumerate the healthcare problems we have and map out a strategy to follow, fix, or live with each one of those issues, and, maybe, a few that still have not yet reared their ugly heads. It may be like herding cats but no one else is going to prevent a stampede.

Activity is at least half the solution. Stay as active as your body can tolerate to keep it from failing prematurely. Run it up, if you don’t want it to run down. It’s a sad fact of life in the West that most of live such soft lives that we’re compelled to schedule exercise if we don’t want to turn into jellyfish. We need to safeguard our calendars to ensure there’s enough physical activity to keep ourselves in the best physical condition we can.

Find an “elder mentor.”  For some reason, we’re under the delusion that we reach a certain age and then stop learning. Or, perhaps more specifically, we no longer need to look for teachers. Getting older means we have to learn new skills, new perspectives, and new habits and that means we have to find new--older--role models. We need to search out the people who seem to be living life older but better than we are and to learn from them. 

We’ve got to let go. If being forty is about being “large and in charge”, whether it be our job or our kids, then getting older is about “peace and release.” It’s about changing our patterns of thinking and reacting. The later decades of our lives are about developing wisdom, generosity, and insight. That begins with letting go of the need to be right and be in control. 

Take time for the affairs of the heart. We need to celebrate the people and things we love. We should never hold a grudge and never go to bed mad. Always give our loved ones a kiss goodbye and a kiss goodnight. And, shoot, let’s forgive ourselves for being the asses we’ve been. 

Last, but perhaps most important, we need to fight back!  Growing old is about combat. It’s about looking mortality in the face, balling up our fists, and then spitting right in its eye. It’s about realizing we’re in for the challenge of our lives and declaring that we will fight for every day of strength, vigor, dignity, and passion that is in our power to wrest free from the gathering conclusion. It’s about defiance, struggle, and courage in the face of a world that may often prejudge, ignore, or condemn us based on our age or appearance. It’s about living defiantly simply because we know we cannot live forever. Living would not require so much courage if it didn’t come to an end. Some may say it’s about learning to close the gap between our dreams and how we live.

So let’s start because this is the youngest we’ll ever be.

Here's the link to the entire article

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